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Cancer drugs trial for when standard treatment is not viable shows 'incredible' signs of success00:00
The best winter fragrances: These warming scents will help to keep the seasonal chill at bay08:47
Thailand beach murders: UK police head to Koh Tao to join investigation after junta leader drops objections17:11
Crystal Palace vs Chelsea match report: Oscar and Cesc Fabregas strike to maintain Chelsea's unbeaten record17:14
Burnley vs West Ham match report: Sam Allardyce's Hammers all present and correct in fourth00:00
Vintage tales of a 700-year-old winery: The Frescobaldi vineyards' extraordinary history00:00
Jack the Ripper: Scientist who claims to have identified notorious killer has 'made serious DNA error'00:00
Stop changing laws behind closed doors, say experts11:18
Paramedics in Ely dumped man's body by bins 'because they wanted to finish work on time'00:00
A diary of modern dining habits: Skype, childcare, work talk ... the evening meal is no longer about the traditional family get-together22:53
X Factor 2014 live show – week 2 review: Chloe Jasmine and Stephanie Nala fall flat15:06
Batman v Superman: Side-kick Robin to be 'woman played by Jena Malone'21:10
Doctor Who, Flatline - review: Clara isn’t half bad as the Time Lord00:00
Himalayas avalanches: Conduct of guides criticised as search for 65 climbers in Nepal goes on00:00
Oscar Pistorius sentence: Athlete's wealth and notoriety provoke an overdue debate on South African prisons12:41
Hurricane Gonzalo puts UK on storm alert as Met Office issues weather warning00:00
A bit of contrition would help, but appallingly behaved footballers barely see a problem00:00
Hong Kong protests: Government resumes talks with demonstrators after police retreat in face of students00:00
Radamel Falcao: How faith and love drive the Manchester United striker to glory00:00
A woman's option to freeze her eggs should never be a job perk00:00
Hugh Bonneville & Peter James: "He has a dash of James Bond derring-do. I lack his panache"00:00
Ebola in the US: Panic over the virus threatens to infect President Obama's midterms00:00
If they can build a giant 'sex toy' in the middle of Paris, then surely anything is possible17:35
US-led coalition jets strike Isis targets in Kobani as militant launch shells across border into Turkey00:00
Boris Johnson's boozing won't win the puritan vote00:00
QPR vs Liverpool: Bobby Zamora determined to stay positive despite speculation over Harry Redknapp's future09:22
Cannabis-eating sheep munch through £4,000 in plants dumped in bag near farm00:00
National service beckons as Fijian-born Semesa Rokoduguni prepares for England call00:00
Joe Bonamassa: The Grammy-nominated blues guitarist on anger, Anglophilia, and his 300 axes00:00
Kidnapped Nigerian schoolgirls: Government claims ceasefire deal with Boko Haram that will bring missing girls home12:06
Paris 'sex toy' Christmas tree sculpture deflated by vandals20:09
Chelsea vs Maribor: Diego Costa a doubt for Champions League clash, reveals Mourinho00:00
Ebola outbreak: WHO missed 'the disaster of our times,' claim aid agencies00:00
Battle against Isis: Plan to charge jihadists with treason 'will not work,' claims terror expert00:00
Bahia: Squabble for world's largest emerald pushes value to £230m00:00
Andrew Selous: 'Disabled are grateful so work harder,' says Tory minister00:00
Inside Lines: Clive Efford emerges from shadows to hit home football goals00:00
Premier League coaches join the RSC to swap the tricks of their trades00:00
New book on Joy Division's Ian Curtis sheds fresh light on the life of the late singer17:28
David Haines memorial: Loved ones pay tributes to 'kind, open and caring' aid worker00:00
Champion Stakes 2014: Noble Mission's victory a salute to the memory of Sir Henry Cecil00:00
Stoke City vs Swansea City: Angel Rangel aiming high to cope with the threat of Peter Crouch00:00
QPR vs Liverpool: Glenn Johnson feels extra burden of Europe is draining Reds00:00
Stoke City vs Swansea City: Mark Hughes anxious to keep his main man Ryan Shawcross00:00
Bury's Joe Thompson winning biggest fight of his life: beating cancer17:56
The Inside Word: Brendan Rodgers looks to the future while Roy Hodgson is ghost of seasons past18:33
Terry Venables: Premier League managers must not be allowed to dictate who plays and who does not play for England00:00
Phone hacking: MPs challenge prosecutors on evidence in Murdoch case00:00
Tell voters the full story about migration and keep hysteria out of the debate00:00
Scientists prove ship's dog on the doomed Mary Rose was male00:00
HS2 rail-link: Stoke readies for fight against Crewe as route for second phase of high-speed line00:00
Staff cuts lead to increase in benefit fraud00:00
My proposal that could keep Britain in Europe00:00
Why David Cameron can't speak up for migration00:00
We owe a debt to Lord Freud00:00
We owe a debt to Lord Freud00:00
Thai scholar may face jail for insulting king who died in 160500:00
Catholic bishops block new guidelines of openness toward gay people00:00
MoD defends new CEO's £500,000 pay that unions label 'utterly outrageous'00:00
Anger grows over Mexico's missing as drug cartels turn to human trafficking00:00
Flagship police policy descends into farce00:00
James Wharton: The former Guard now fighting discrimination against gay soldiers00:00
Fanfare for fabric as two major London galleries put textiles in the spotlight00:00
Eric Pickles accused of 'rejecting wind farms to win votes'00:00
M&S Female has a new champion – a woman just like her00:00
New minicab law 'would put women at risk'00:00
Health tourism clampdown 'puts public at risk,' claims think-tank00:00
Shortage of fish 'stops poor from eating healthily'14:57
Back To The Future producer and co-writer says there are no plans to ever reboot the classic film19:58
Racing Metro 20 Northampton 11 match report: Saints throw away the bonus point after Racing’s Andreu pounces late on19:47
Round-up: Ricardo Fuller strikes twice as Millwall thwart old boss22:30
Louis van Gaal: I want England to pick my Manchester United lads for Under-21s19:53
Book of the week: Football Clichés by Adam Hurrey19:51
Glasgow Warriors vs Bath match report: Mark Bennett leads a highland charge19:41
Cardiff City vs Nottingham Forest match report: Slade’s debut ends Forest’s unbeaten start19:38
Birmingham City vs Bolton Wanderers match report: Lively Neil Lennon picks up debut win and a red card19:35
Arsenal vs Hull: Defender watch17:16
Arsenal vs Hull match report: Danny Welbeck’s leveller holds the fans’ revolution at bay18:16
Newcastle vs Leicester City match report: Gabriel Obertan ensures Newcastle pass their screen test19:21
Southampton vs Sunderland: Keeping score - as the goals went in00:00
Too much on our plates: Britain is utterly spoilt by food00:00
Caffeine overload: Shots heard around the world00:00
When did Donald Trump become a statesman?00:00
Trapped in a bookshop? My idea of heaven00:00
Shareholders are the only ones who can heal capitalism now00:00
IoS letters, emails & online postings (19 October 2014)17:13
Mexican authorities arrest notorious gang leader over disappearance of 43 students17:46
Saracens vs Clermont match report: Chris Ashton and David Strettle at the double as Sarries cut loose18:32
Dewani killer dead in prison: Hit man Xolile Mngeni dies of cancer11:59
Premier League live: Arsenal vs Hull, Crystal Palace vs Chelsea, Everton vs Aston Villa, Southampton vs Sunderland and more12:00
Tim Minchin, interview: The musician, comedian and world's favourite ginger is on scorching form00:00
Sean Harris: A rare interview with British acting's secret weapon15:49
Britain's rainiest cities revealed – and it's good news for Londoners17:23
Siding Spring: How to watch comet's close encounter with Mars live10:54
Himalayas avalanches: British woman Lizi Hamer and partner are 'safe and sound' in Nepal17:10
International Space Station visible to the naked eye above UK this evening17:09
Everton vs Aston Villa match report: Romelu Lukaku hastens Villa decline by winning battle of Belgians16:01
In numbers: Why so many people believe Britain needs a pay rise09:40
Ebola outbreak: World Health Organisation botched initial handling16:15
Percy Harvin traded to New York Jets: Seattle Seahawks trade Super Bowl winner for a first round draft pick16:10
Ebola outbreak could be 'definitive humanitarian disaster of our generation', warns Oxfam16:02
In pictures: The hurricane that could be headed for Britain16:05
Manchester City 4 Tottenham 1: Five things we learned16:03
Miss Hitler 2014: Yes, there really is a neo-Nazi beauty contest in Russia15:58
Theo Walcott completes 45 minutes for Arsenal Under-21s on his return from injury13:21
Pay protests: Thousands march for better wages as unions demonstrate across Britain15:53
WWE Smackdown Results: Tensions boil between Dean Ambrose and Seth Rollins before their battle at Hell in a Cell15:16
Manchester City 4 Tottenham 1 player ratings: Could anyone come close to Sergio Agureo?14:48
Newcastle v Leicester: Match delayed by an hour due to 60m big screen being dislodged by the wind13:19
Nicola Sturgeon sells out venues across Scotland in first appearances as SNP leader13:20
Stricken Russian ship Simushir off Canadian coast could lead to environmental disaster14:25
Colorado police warn marijuana sweets may end up in children's Halloween trick-or-treat bags14:18
Crystal Palace v Chelsea team news: No Diego Costa for the Blues as Willian and Loic Remy start14:19
Arsenal vs Hull team news: Hector Bellerin starts for Gunners as Aaron Ramsey makes shock return among substitutes13:24
South Korea music festival disaster: Organiser of pop concert that claimed 16 lives is found dead13:51
Cannibal harlequin ladybirds now threaten native species with STDs13:56
Manchester City vs Tottenham: Manuel Pellegrini has no fears over Ebola virus despite Yaya Toure visiting West Africa mid-week13:18
Iraq's 'most-wanted' playing cards go on display at the Pentagon12:09
Manchester City v Tottenham team news: Yaya Toure on the bench for City while Roberto Soldado starts for Spurs13:39
Manchester City vs Tottenham half-time match report: Sergio Aguero strikes twice but misses easy chance for 32-minute hat-trick13:32
Mother 'sewed daughter's lips together and forced her to eat cat litter'13:36
Britons 'most happy at 58'13:11
Jeremy Clarkson admits getting speeding points on his driving licence13:19
Russian Tennis Federation president fined for 'Williams brothers' comments11:18
Owners of vicious and nuisance dogs face fines up to £20k if they fail to curb behaviour13:06
Australia vs New Zealand: All Blacks secure last-gasp victory as Ewen McKenzie resigns as Wallabies head coach a year out from World Cup12:27
Ched Evans: Sheffield United deny offering new contract to convicted rapist after his release from prison12:37
US company sells out of Ebola-themed toys12:17
Editor's Letter: Who will dare to be honest about our deficit?12:15
The Manhattan Transfer founder Tim Hauser dies aged 7212:13
Arsenal vs Hull: Arsene Wenger 'ready to fight on' as 65th birthday looms next week09:38
One-week cancer tests paid for by tax on tobacco firms, Labour promises00:00
Rotherham child abuse scandal: Missing files 'fuel public suspicion of a deliberate cover-up’, say MPs11:30
Edinson Cavani sent off after celebrating penalty with gun gesture in PSG's bad-tempered victory over nine-man RC Lens10:21
Man's body discovered on M5 carriageway00:00
Ebola - the global response: Promises, promises – but still just a trickle of real help10:01
President Obama's credit card declined in New Yok cafe: 'But I really have been paying my bills'00:00
How to dress with authority: Kirsty Wark and Camila Batmanghelidjh discuss the changing role of fashion in women's workwear00:00
Ash frontman Tim Wheeler reveals how he came to terms with his father's dementia00:00
Bill Granger recipes: Our chef's heavenly crab dishes don't need hours of preparation00:00
Wines of the week: The best Languedoc-Roussillon bottles00:00
Middle Class Problems: Staying in a stranger's home is incredibly awkward ... but it has become de rigeur00:53
Hurricane Gonzalo: High winds and heavy rain set to lash parts of Britain00:00
Danny Alexander pips Vince Cable to Lib Dem campaign role of economic spokesman00:06
The Sport Matrix: Saturday 18 October 201400:00
The News Matrix: Saturday 18 October 201400:01
David Haines's and Alan Henning's families call for 'acts of unity' in face of Isis threats00:00
Postcard from... New York00:00
Black magic: Move over to fashion's dark side this winter with monochrome menswear00:00
Rick Owens and the dark art of creativity: "I could just burn the whole f*****g place down"00:00
Michael Howells: The film and fashion set designer on Instagram, working with John Galliano and Gary Cooper's nonchalant style00:00
Hollywood's men in black: A history of cinema's favourite colour from Brando to The Matrix00:00
Fabien Baron goes to Greenland: The creative director has trained his Leica on the Arctic Circle's monumental ice floes00:00
Mark Hix recipes: From baked shallots to hearty soup, our chef know his onions00:00
A-list winter looks: Eight must-have menswear items viewed through a cinematic lens00:00
Charlotte Philby's Parental Leave: "My friend tells me Geordies hate people from London"00:00
Rhodri Marsden's interesting objects: The 1843 Millerite chart00:00
Anthony Rose: "Independent wine merchants are often leagues ahead of the supermarkets"00:00
Wine: Curator's Choice White; Cuvée d'Automne, St Joseph, Northern Rhône; Vasse Felix Heytesbury Margaret River Chardonnay00:00
Are Government Acts still translated into Norman French?00:00
Manchester House, restaurant review: Is Aiden Byrne's culinary wizardry just an illusion?00:00
Paperback reviews: My Age of Anxiety, Still Life with Breadcrumbs, A Story Lately Told, Falling, The Boarding House00:00
Emma Townshend: "It's pouring out there - and it couldn't make me happier"00:00
The top ten: Old words that sound new12:00
The love song of Miss Queenie Hennessy by Rachel Joyce, book review: Companion piece to The Unlikely Pilgrimage of Harold Fry is a wonderful read00:00
The Diarists: This week in history12:00
The Assassination of Margaret Thatcher by Hilary Mantel, book review: Author conjures sinister forces12:00
Book reviews on the environment: Don't Even Think about it by George Marshall and This Changes Everything by Naomi Klein00:00
DJ Taylor: There are a few Soho watering places where veteran bohemian Liza Radley and her cronies are still welcome12:00
Evil Eye by Joyce Carol Oates, book review: An extraordinarily vivid depiction of lives gone awry00:00
Giovanni Battista Moroni, Royal Academy, preview: All hail to a dedicated follower of fashion00:00
The best grooming products for men: There are a wealth of lotions and potions designed to appeal to a gent's olfactory senses00:00
Alison Taylor on relationships: What are the politics of hand-holding for us normal folk?00:00
Lima Floral, restaurant review: Does Martinez's sister venture have the same wow factor?00:00
All Good Things: Baracuta jackets; Pact coffee beans; Neom Organics's mood-lifting oils00:00
Tim Key: Eating pizza in Manchester can be Hell00:00
The Saturday Quiz answers00:00
The Saturday Quiz: Try our weekly brain teaser00:00
The Novel Cure: Literary prescriptions for being too organised00:00
Sophie Kinsella, novelist: 'All of my own heroines have a snippet of me somewhere'00:00
Palo Alto, film review: Gia Coppola and talented cast bring James Franco's small dramas to life00:00
The Bonus Track: Cale Tyson, Rae Morris, Jake Thackray, Taylor Swift