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An airstrike has killed at least 54 people in an Isis -held area of Syria near the border with Iraq, a war monitor has said.
The Syrian Observatory for Human Rights as well as pro-Syrian government news outlets said the US-led coalition carried out the strike near the town of Al Bukamal, east of the Euphrates river, late on Thursday night.
Sana, Syria’s state news agency, put the number of dead at 30 in bombings which hit the villages of al Sousa and al Baghouz Fawkani on the river’s banks. In al Sousa, it is believed the strike hit families using an old ice factory as shelter.
Isis militants are also believed to be among the death toll.
Raqqa's fall: A journey into the heart of Isis’ failed caliphate US Central Command said it may have carried out bombings “in the vicinity” of the area.
US forces, the Iraqi air force and Western partners are still launching air support in eastern Syria to assist the Arab-Kurdish coalition Syrian Democratic Forces (SDF), in crushing the remnants of Isis.
The international coalition has been repeatedly criticised by human rights watchdogs for not taking adequate care to protect civilians in the colossal airstrikes which have helped destroy the extremist group.
In Pictures: The crisis unfolding in SyriaShow all 30 1 /30In Pictures: The crisis unfolding in Syria In Pictures: The crisis unfolding in Syria A Syrian family arrives at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods
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In Pictures: The crisis unfolding in Syria A Syrian woman, fleeing violence in the restive Bustan al-Qasr neighbourhood, reacts as she stands with her children in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past resident fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said
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In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood , after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past residents fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria A Syrian pro-regime fighter speaks with a child, as residents flee violence in the restive Bustan al-Qasr neighbourhood. Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops
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In Pictures: The crisis unfolding in Syria Smoke rises as seen from a governement-held area of Aleppo, Syria
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In Pictures: The crisis unfolding in Syria Syrian soldiers targeting rebels-held areas in the eastern neighborhoods in Aleppo, Syria. According to media reports, the army is now holding on 99 percent of Aleppoís eastern neighborhoods
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In Pictures: The crisis unfolding in Syria Syrian pro-government forces patrol Aleppo's eastern al-Salihin neighbourhood after troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian soldiers rest following the battle at al-Sheik Saeed neighborhood in Aleppo, Syria
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In Pictures: The crisis unfolding in Syria A Syrian pro-government fighter walking past closed shops in the Bab al-Nasr district of Aleppo's Old City. Once renowned for its bustling souks, grand citadel and historic gates, Aleppo's Old City has been rendered virtually unrecognisable by some of the worst violence of Syria's war
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In Pictures: The crisis unfolding in Syria The crucial battle for Aleppo entered its 'final phase' after Syrian rebels retreated into a small pocket of their former bastion in the face of new army advances. The retreat leaves opposition fighters confined to just a handful of neighbourhoods in southeast Aleppo, the largest of them Sukkari and Mashhad
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In Pictures: The crisis unfolding in Syria Syrian civilans arrive at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods. Syria's government has retaken at least 85 percent of east Aleppo, which fell to rebels in 2012, since beginning its operation
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In Pictures: The crisis unfolding in Syria Syrian civilians flee the Sukkari neighbourhood towards safer rebel-held areas in southeastern Aleppo
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In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances
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In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances. The fall of Aleppo would be the worst rebel defeat since Syria's conflict began in 2011, and leave the government in control of the country's five major cities
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In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria Syrian refugee Aliya inside the tent where she lives with her husband and ten children in a camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria Syrian refugee women and children outside the entrance to their tents in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria A Syrian refugee woman outside the entrance to the tent where her family live, in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
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In Pictures: The crisis unfolding in Syria A vehicle drives past a mosque at night in Idlib, Syria. Picture taken with a long exposure
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In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled town of Binnish in Idlib province, Syria
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In Pictures: The crisis unfolding in Syria The night sky is seen through damaged windows in the rebel-controlled town of Binnish in Idlib province, Syria
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In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled area of Maaret al-Numan in Idlib province, Syria
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Officials admitted last year that strikes against Isis in both Syria and Iraq since 2014 have killed at least 800 civilians, but credible monitoring teams put the toll at at least 6,000 people.
Although the so-called caliphate has largely collapsed, there are still believed to be around 8,000 to 10,000 Isis fighters active in the desert on the Syria-Iraq border.
Recent deadly attacks on their former Syrian stronghold of Raqqa have raised fears the militants are regrouping as an insurgency movement.
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