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Mpox virus latest: WHO calls for $135 million fund to stop outbreaks as new strain mutating rapidly

Scientists “don’t understand” the latest outbreak of the Clade Ib Mpox variant

Salma Ouaguira,Alex Croft
Tuesday 27 August 2024 11:12 BST
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The public health emergency was declared by the WHO director general Dr Tedros Adhanom Ghebreyesus

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The World Health Organisation (WHO) has called for $135 million funding to combat the Mpox strain outbreak, which scientists say is mutating “more rapidly” than expected.

On August 14, the organisation declared an Mpox-related global health emergency for the second time in two years.

Speaking to WHO member states, Director-General Tedros Adhanom Ghebreyesus said the latest outbreak “can be controlled and can be stopped”.

$135 million of funding will be needed over the next six months to halt the outbreak, an amount which will “likely increase” over time, Mr Ghebreyesus added.

Scientists have expressed concern at the rate at which the current Mpox strain, Clade Ib, is mutating.

Nigerian scientist Dr. Dimie Ogoina said they “don’t understand the outbreak very well”, leading to difficulty in addressing the disease’s transmission and severity.

Seattle-based doctor Dr. Miguel Paredes said the virus is mutating “more rapidly than we would expect”.

Democratic Republic of Congo has faced the brunt of the outbreak, which has also spread to Burundi, Central African Republic, Rwanda, and Uganda.

The UK is readying itself after Sweden reported Europe’s first case of the deadly variant. Three days ago, Thailand confirmed Asia’s first suspected case of the variant.

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Singapore confirms 13 cases detected of mpox Clade 2

Singapore has detected 13 cases of mpox Clade 2 this year, the health ministry said on Thursday.

All mpox infections so har have been “less severe”, the ministry added.

Thailand also confirmed an mpox case this week, the second case of the variant confirmed outside Africa.

Salma Ouaguira23 August 2024 10:03
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Salma Ouaguira23 August 2024 09:30
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Thailand confirms Asia’s first known case of dangerous new mpox variant

Thailand has confirmed Asia’s first known case of a new, more dangerous strain of mpox in a European traveller.

The patient, a 66-year-old man who arrived from an unnamed African country on 14 August, has tested positive for the Clade 1b variant, which is deadlier and more transmissible.

“Thailand’s Department of Disease Control wishes to confirm the lab test result which shows mpox Clade 1b in a European patient,” the department said in a statement.

The man had minimal contact with other people after he arrived in Thailand and sought medical attention the following day after he experienced symptoms similar to mpox, authorities said.

Read the full story below:

Thailand confirms Asia’s first known case of dangerous new mpox variant

European man, 66, arrived in Thailand from an unnamed African country on 14 August

Salma Ouaguira23 August 2024 09:00
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How is mpox spread?

The outbreak comes as a new strain is identified, named clade 1, said to be spreading mainly through sexual networks.

WHO says it has been identified in Burundi, Kenya, Rwanda and Uganda – all countries that have never reported cases of mpox before.

Although mpox was not generally a sexually transmitted infection in 2022-23, it was suggested by public health officials that the outbreaks were linked to sexual activity - with the majority, but not all, cases amongst men who have sex with men.

Salma Ouaguira23 August 2024 08:30
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Pictured: Mpox prevention at internally displaced persons camps in Goma

Cross workers raise awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma, Democratic Republic of Congo
Cross workers raise awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma, Democratic Republic of Congo (EPA)
A Red Cross worker sprays chlorine as other Red Cross personnel raised awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma
A Red Cross worker sprays chlorine as other Red Cross personnel raised awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma (EPA)
Red Cross workers raise awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma
Red Cross workers raise awareness about mpox and hygiene among internally displaced people in the Don Bosco camps in Goma (EPA)
Salma Ouaguira23 August 2024 08:00
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Isle of Man ‘planning and preparing’ for mpox outbreak but risk remains ‘low’

People on the Isla of Man have been urged to remain vigilant about symptoms of mpox as the dangerous strain spreads.

The island’s public health officials said it was “planning and preparing” to deal with any cases but the risk to residents were still “low”.

A case of the deadly virus Clade Ib was detected in Sweden last week.

The World Health Organisation declated the outbreaks originating from Democratic Republic of the Congo a public health emergency of international concern.

Salma Ouaguira23 August 2024 07:30
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Why has the WHO declared a global emergency?

Mpox was first detected in humans in the DRC in 1970 and is considered endemic to countries in Central and West Africa.

However, WHO said the recent surge of cases in DRC and its spread to neighbouring countries constitutes a public health emergency of international concern (PHEIC) under the International Health Regulations (2005) on Wednesday.

According to WHO, mpox has been reported in DRC for more than 10 years, with the number of cases increasing steadily over the period.

So far in 2024, there have been more than 15,600 cases of mpox and 537 deaths, which the WHO said exceeds last year’s total.

There have also been 100 lab-confirmed cases of clade 1b in four countries neighbouring the DRC that have not reported mpox before: Burundi, Kenya, Rwanda and Uganda.

Salma Ouaguira23 August 2024 07:00
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What is mpox? What you need to know about the latest global health emergency

What is mpox and why has it been declared a global health emergency?

More than 14,000 cases and 524 death have been reported from mpox in Africa this year

Salma Ouaguira23 August 2024 06:00
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Bavarian Nordic to boost mpox vaccine production to tackle outbreak

Danish biotech firm Bavarian Nordic could ramp up production of its mpox vaccine even before having orders lined up, based on the outcome of talks this week with the World Health Organisation, the company’s CEO told Reuters.

Chief Executive Officer Paul Chaplin said in an interview that the company urgently needs to make the call on whether to manufacture “at risk” - or without signed contracts - because diverting or switching manufacturing capacity from its other vaccines to mpox will take time.

In order to make that decision, Bavarian Nordic “would need to be reasonably convinced that those orders would be coming through”, Chaplin said.

“We’ll have to wait and see how the discussions develop this week and we’ll make a decision later this week what we’re doing.”

He said the discussions were with the WHO, the global vaccine group Gavi, and the Africa Centres for Disease Control and Prevention (CDC), and with individual governments in Africa and elsewhere.

It comes as the company said on Saturday it has informed the Africa CDC that it could manufacture 10 million doses of the vaccine by the end of 2025, and could supply up to 2 million doses this year.

But the 2 million doses by year-end would not be possible unless Bavarian Nordic “changes gears” to start producing more of its mpox vaccine now, instead of its other vaccines, Chaplin said: “Every week we don’t switch over, we lose some of that capacity.”

An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany
An employee of the vaccine company Bavarian Nordic works in a laboratory of the company in Martinsried near Munich, Germany (REUTERS)
Salma Ouaguira23 August 2024 05:00
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Travellers urged to get mpox vaccine before going to impacted areas of Africa

People travelling to areas affected by the recent mpox outbreak in Africa have been urged to get vaccinated by the EU’s public health body.

European Centre for Disease Prevention and Control (ECDC) updated its advice to people going to “epidemic areas” to “consult their healthcare provider or travel health clinic regarding eligibility for vaccination against mpox”.

The ECDC said it is “highly likely” that Europe will have “more imported cases of mpox caused by the clade 1 virus currently circulating in Africa”.

Read the full story below:

Travellers urged to get mpox vaccine before going to impacted areas of Africa

 European Centre for Disease Prevention and Control says more important cases in Europe is ‘highly likely’

Salma Ouaguira23 August 2024 04:00

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