Stay up to date with notifications from The Independent

Notifications can be managed in browser preferences.

Diabetes medication can cut risk of heart failure by more than a quarter, scientists find

Well-known diabetes drug can cut causes of death by heart failure, scientists find in large-scale study

Conor Riordan
Monday 02 September 2019 07:18 BST
Comments
Dapagliflozin was also found to benefit patients without diabetes
Dapagliflozin was also found to benefit patients without diabetes (Getty)

Your support helps us to tell the story

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.

At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.

The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.

Your support makes all the difference.

A common diabetes medication can be used to treat patients with heart failure, according to new research.

Scientists have found dapagliflozin – a drug that helps control blood sugar levels – can also reduce the risk of cardiovascular conditions worsening or causing death by more than 25 per cent.

The medicine also cut the chances of death from any cause by 17 per cent in patients with established heart failure and hospital admission with worsening heart failure by 30 per cent.

John McMurray, professor of cardiology at the University of Glasgow, said: “These are really once in a lifetime findings that show that a commonly prescribed drug for diabetes can effectively be used to treat people with heart failure.

“Probably the most important finding of all is that dapagliflozin was associated with benefit in patients without diabetes.

“With dapagliflozin, we did the three things you want to do for the patient in the ideal world – make them feel better, keep them out of hospital and keep them alive. That’s why we’re so delighted with the results.”

Dapagliflozin is known to effectively treat diabetes and also reduce the risk of these patients developing heart failure – a common complication of type 2 diabetes.

In this study, researchers wanted to find out whether the same medication could effectively treat patients already diagnosed with heart failure, whether they had the condition or not.

The trial looked at 4,744 patients from 20 countries around the world.

Researchers then measured the effectiveness of the drug against a placebo.

Around half of the patients enrolled in the trial did not have diabetes.

PA

Join our commenting forum

Join thought-provoking conversations, follow other Independent readers and see their replies

Comments

Thank you for registering

Please refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in