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Syrian government air strikes and artillery attacks killed at least 71 people in a rebel enclave near Damascus over the past 24 hours, a monitoring group has said.
The Britain-based Syrian Observatory for Human Rights said the bombardment of eastern Ghouta intensified on Sunday evening, wounding 325 people.
The death toll included at least five children, the Observatory said.
Eastern Ghouta , the largest rebel bastion left near the capital, is home to almost 400,000 people according to the United Nations and has been besieged since 2013.
Rebel groups in eastern Ghouta fired mortars at areas of Damascus held by the government, killing a child and injuring eight other people, Syrian state media said.
In Pictures: The crisis unfolding in SyriaShow all 30 1 /30In Pictures: The crisis unfolding in Syria In Pictures: The crisis unfolding in Syria A Syrian family arrives at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods
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In Pictures: The crisis unfolding in Syria A Syrian woman, fleeing violence in the restive Bustan al-Qasr neighbourhood, reacts as she stands with her children in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past resident fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said
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In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood , after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past residents fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood
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In Pictures: The crisis unfolding in Syria A Syrian pro-regime fighter speaks with a child, as residents flee violence in the restive Bustan al-Qasr neighbourhood. Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops
AFP/Getty Images
In Pictures: The crisis unfolding in Syria Smoke rises as seen from a governement-held area of Aleppo, Syria
Reuters
In Pictures: The crisis unfolding in Syria Syrian soldiers targeting rebels-held areas in the eastern neighborhoods in Aleppo, Syria. According to media reports, the army is now holding on 99 percent of Aleppoís eastern neighborhoods
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In Pictures: The crisis unfolding in Syria Syrian pro-government forces patrol Aleppo's eastern al-Salihin neighbourhood after troops retook the area from rebel fighters
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In Pictures: The crisis unfolding in Syria Syrian soldiers rest following the battle at al-Sheik Saeed neighborhood in Aleppo, Syria
EPA
In Pictures: The crisis unfolding in Syria A Syrian pro-government fighter walking past closed shops in the Bab al-Nasr district of Aleppo's Old City. Once renowned for its bustling souks, grand citadel and historic gates, Aleppo's Old City has been rendered virtually unrecognisable by some of the worst violence of Syria's war
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In Pictures: The crisis unfolding in Syria The crucial battle for Aleppo entered its 'final phase' after Syrian rebels retreated into a small pocket of their former bastion in the face of new army advances. The retreat leaves opposition fighters confined to just a handful of neighbourhoods in southeast Aleppo, the largest of them Sukkari and Mashhad
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In Pictures: The crisis unfolding in Syria Syrian civilans arrive at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods. Syria's government has retaken at least 85 percent of east Aleppo, which fell to rebels in 2012, since beginning its operation
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In Pictures: The crisis unfolding in Syria Syrian civilians flee the Sukkari neighbourhood towards safer rebel-held areas in southeastern Aleppo
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In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances
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In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances. The fall of Aleppo would be the worst rebel defeat since Syria's conflict began in 2011, and leave the government in control of the country's five major cities
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In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA wire
In Pictures: The crisis unfolding in Syria Syrian refugee Aliya inside the tent where she lives with her husband and ten children in a camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA wire
In Pictures: The crisis unfolding in Syria Syrian refugee women and children outside the entrance to their tents in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA Wire
In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA wire
In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA Wire
In Pictures: The crisis unfolding in Syria A Syrian refugee woman outside the entrance to the tent where her family live, in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border
PA wire
In Pictures: The crisis unfolding in Syria A vehicle drives past a mosque at night in Idlib, Syria. Picture taken with a long exposure
Reuters
In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled town of Binnish in Idlib province, Syria
Reuters
In Pictures: The crisis unfolding in Syria The night sky is seen through damaged windows in the rebel-controlled town of Binnish in Idlib province, Syria
Reuters
In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled area of Maaret al-Numan in Idlib province, Syria
Reuters
Syria's President, Bashar al-Assad, has gained momentum in the war since Russia entered on his side in 2015, pushing the rebels from big cities and retaking much of central and eastern areas of the country from Isis.
Though he appears to have survived the insurgency, his forces continue to bomb and besiege opposition pockets across Syria.
Opposition activists say government forces have brought in reinforcements in preparation for a wide offensive on the last main rebel stronghold near the capital.
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